بررسی میزان ابتلاء به عفونت های پس از ترانسفوزیون در کودکان تالاسمیک شهر همدان

This cross-sectional   descriptive   analytic   study  was  carried   out  for     evaluation of posttransfusion infections (Hepatitis B,C and Aids) in children     suffering major thalassemia who were transfused repeatedly. The  relation     of liver inflammation and number of blood transfusions were studied.           A check list was completed for each case. ALT, HBsAg , anti-HCV  and     anti-HIV tests were preformed for all of 53 children. Population were  fifthy     three   major   thalasemic   children   under   15   years   old  in   Hamadan     provience.           Twenty two  out of  53 children (41.5%) had  elevated  ALT, 18  patients     (34%) had positive anti-HCV. In all of 18 patients with positive anti-HCV,ALT     was also  elevated  , all  of the patients were negative for anti-HBsAg and     anti-HIV.           Determination of ALT level of the donated blood is useful for detection     of chronic hepatitis. This test can be used as an easy screening tool.